Biological organisms showcase a stunning array of diversity, yet they represent only an infinitesimal proportion of possible permutations. We want to understand the course of evolution and the role that physical and chemical constraints may play. Using experiment, theory, and simulation, we analyze simple (bio)chemical systems at the edge of life. Such systems can also help us understand the origins and early evolution of life.

Recent news:

Information-driven mechanism overcomes chemical biases

Dr. Sudha Rajamani joins faculty of IISER Pune

The genetic takeover: why switch from RNA to DNA?

Phage protein inhibits bacterial conjugation

Kevin Leu wins Hoopes Prize for undergraduate thesis

Dr. Julien Derr to join faculty of the University of Paris 7

Kevin Leu wins the 2010 Novartis Undergraduate Research Award

Wired: Origin of Life Chicken-and-Egg Problem Solved